Results 161 to 170 of about 50,085 (301)

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia   +3 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

Young children's right to be heard on the quality of their education: Addressing potential misunderstandings in the context of early childhood education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract In early childhood education many researchers and professionals across the world have embraced the United Nations Convention on the Rights of the Child's requirement to include young children in decision‐making. In the context of ongoing discussion about young children's capacity to share their views and opinions about matters affecting them ...
Laura Lundy   +3 more
wiley   +1 more source

Putting the new aid paradigm to work: challenges for monitoring and evaluation [PDF]

open access: yes
Over the last few years a remarkable shift has taken place in the aid instruments advocated for low-income countries, characterised by a conversion from project to more programme oriented aid and by the inclusion of 'broad-based civil society ...
Holvoet, Nathalie, Renard, Robrecht
core   +1 more source

Why do people choose to enter and exit the teaching profession? An interdisciplinary quantitative synthesis

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Many nations experience recurring shortages of teachers in particular subjects, prompting concerns that pupils' education is suffering as a result. Researchers have responded by generating a sizable literature on the reasons for which people enter and exit the teaching profession.
Sam Sims   +2 more
wiley   +1 more source

Understanding teacher agency in the context of school‐based climate change and sustainability education: A case study of the experiences of teachers and school students in England

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Drawing on teacher agency as a conceptual framework, we explored the extent to which school teachers in secondary schools in England achieve agency in relation to teaching climate change and sustainability. This research provides a novel approach to understanding the relational and emergent qualities of teacher agency by bringing together ...
Nicola Walshe, Elizabeth A. C. Rushton
wiley   +1 more source

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