Results 181 to 190 of about 4,334 (258)

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui   +12 more
wiley   +1 more source

Popular health surveillance in the face of climate emergencies. [PDF]

open access: yesPLOS Glob Public Health
Carneiro FF   +7 more
europepmc   +1 more source

Ultrafast Chemical Pre‐Sodiation of Pseudocapacitive CaV8O20 Anodes for High‐Performance Sodium‐Ion Capacitors

open access: yesAdvanced Science, EarlyView.
An ultrafast (2‐minute), gas‐free chemical pre‐sodiation strategy using Na‐benzophenone is developed to compensate for initial sodium loss in calcium vanadate (CaV8O20). Driven by the Ca2+ ‘spectator effect’, the framework enables highly reversible, quasi‐zero‐strain solid‐solution sodium storage, explicitly bypassing destructive conversion reactions ...
Neetu Bansal   +7 more
wiley   +1 more source

A Good Society (and how we make it). [PDF]

open access: yesJ Epidemiol Community Health
Pickett KE.
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

open access: yesAdvanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi   +11 more
wiley   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

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