Results 121 to 130 of about 208,329 (308)

Collective Interview on the History of Town Meetings [PDF]

open access: yes, 2019
As illustrated in the introduction, the special issue ends with a ‘collective interview’ to some distinguished scholars that have given an important contribution to the study of New England Town Meetings.
Bryan, F.   +11 more
core  

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

open access: yesAdvanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang   +7 more
wiley   +1 more source

On Information Society and Democracy

open access: yesTürk Kütüphaneciliği, 2013
Information society with the underlying communication technology revolution was assumed to contribute to democracy. The glittering words such as participatory  democracy, direct democracy, tele-democracy, e-government, e-democracy are now a part of our ...
Kadri Yamaç
doaj  

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Is The Daily Show Bad for Democracy? An Analysis of Cynicism and its Significance [PDF]

open access: yes, 2012
In recent years, satirical news programs like The Daily Show with Jon Stewart have emerged as an important development in contemporary American society, culture, and politics. Critics have argued that The Daily Show has a negative impact on the political
Bartlett, Evan
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Coerced transitions in Timor-Leste and Kosovo [PDF]

open access: yes, 2011
Statebuilding under the aegis of international administrations has faced various hurdles and obstacles in Kosovo and Timor-Leste. One of these hurdles is related to the specific mandate of these missions, which created a specific conflict of objectives ...
Lemay-Hebert, Nicolas
core  

Capture and Culture of Circulating Tumor Cells Using a Biodegradable 3D Scaffold for Patient‐Derived Xenograft Construction

open access: yesAdvanced Science, EarlyView.
A self‐supporting, biocompatible, and biodegradable 3D cellulose scaffold has been developed for efficient isolation and in situ expansion of circulating tumor cells (CTCs) from patient blood. Subsequently, the 3D cellulose scaffold with cultured CTCs is directly implanted into immunodeficient mice for constructing patient CTC‐derived xenograft (CDX ...
Yi‐Ke Wang   +9 more
wiley   +1 more source

Os sentidos e desafios da participação

open access: yesCiências Sociais Unisinos, 2006
This article analyzes some challenges and difficulties of the participatory experiences in Brazil – particularly of the Managing Councils and the Participatory Budgeting – in constituting themselves as experiences of deliberative democracy.
Lígia Helena Hahn Lüchmann
doaj  

Home - About - Disclaimer - Privacy