Results 141 to 150 of about 836,137 (285)

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

Participatory democracy and ius impositionis

Nowadays, among the powers that characterize state sovereignty, the power to withdraw wealth to meet public expenses and needs of the community takes on a completely peculiar dimension.
Parente Salvatore Antonello
core  

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

The Futures of Digital Democracy: Four Scenarios. [PDF]

Open Res Eur
Fuchs C, Museba J, Friesch K.
europepmc   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source

Polyelectrolyte Multilayer: Caged PTFE Particles in Water for Continuous, Sonochemical H2O2 Synthesis

Advanced Science, EarlyView.
A yolk–shell PTFE‐based composite (YSP) enables tunable, robust hydrophobic–water interfaces for efficient, on‐demand sonocatalytic H2O2 generation and pollutant degradation. ABSTRACT The use of polytetrafluoroethylene (PTFE) particles to promote sonochemical H2O2 production has attracted growing interest, as cavitation bubbles formed at or near their ...
Rong Wang, Bo Wang, Tengyue Fu, Yue Yang, Chongling Cheng, Zhenhui Qi, Dayang Wang   +6 more
wiley   +1 more source

How Bioethicists Can Contribute to Democratic Deliberation. [PDF]

Bioethics
Saunders B.
europepmc   +1 more source

Geometry‐Regulated Electrode‐Wide Nucleation Patterns in Aqueous Zinc Anodes

Advanced Science, EarlyView.
Laser‐ablated 3D hole patterning enables geometry‐driven control of Zn deposition in aqueous batteries. The hole opening ratio (HOR) governs electrode‐wide nucleation patterns by regulating the spatial distribution of nucleation sites and the evolution of early‐stage Zn deposits.
Seyoung Han, Taehyun Lee, Haeun Kim, Ji Hyun Um, Dongkyoung Lee   +4 more
wiley   +1 more source

ACTIVE involvement in alcohol care: a community case study in coproduction. [PDF]

Front Public Health
Best V, Bryan L, Edmunds S, Kitch N, Sastre E, Wells K, McNeice M, Owens L, Smith M, Menghani R, Sharp H, Richardson P, Garner J, McKeown M.   +13 more
europepmc   +1 more source