Results 61 to 70 of about 1,386,178 (330)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

From Political Clientelism to Participatory Democracy

Engagement: Jurnal Pengabdian Kepada Masyarakat, 2022
The Act of Village has given many opportunities for villages in Indonesia to generate innovation in the local contexts. The governance for village development creates a new way to develop the rural area through visionary leadership innovation. This study
Abdur Rozaki
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Citizens’ deliberations and the EU democratic deficit – Is there a model for participatory democracy? [PDF]

, 2008
There is a longstanding debate on the EU’s democratic deficit. Recently, the EU has responded to this by including the idea of participatory democracy in the Lisbon treaty. This corresponds to first experiments with means for citizens’ participation that
Abels, Gabriele.
core  

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun, Shaun G. Hong, Na Young Park, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Más allá de la democracia representativa: La democracia real y los movimientos sociales en el Estado español

Revista Crítica de Ciências Sociais, 2017
Participatory processes are a central element in the theoretical debates on the quality of democracy and its current processes of transformation. If the objective of participation is problematized in theoretical analyses, difficulties increase when ...
Marina Requena Mora, José Manuel Rodríguez Victoriano   +1 more
doaj   +1 more source

Schooling for Democracy [PDF]

, 2011
oai:democracyeducationjournal.org:home-1000There is a widespread movement today to prepare all students for college, and it is promoted in the name of democracy.
Noddings, Nel
core   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Practice of Participatory Governance in Public Policy

RUDN Journal of Political Science, 2018
This article examines the idea of participatory democracy. The article provides case study of pilot projects aimed to engage citizens for public participation in different forms, such as: participatory budgeting, participatory modeling, public ...
Alyona S Perezolova
doaj   +1 more source