Results 31 to 40 of about 209,579 (354)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Reforming the Relationship between the State and Civil Society in Latin America

open access: yesLatin American Research Review, 2018
This essay reviews the following works: Enhancing Democracy: Public Policies and Citizen Participation in Chile. By Gonzalo Delamaza. New York: Berghahn Books, 2015. Pp. vi + 296. $99.00 hardcover. ISBN: 9781782385462. The Politics of Local Participatory
Maureen Donaghy
doaj   +1 more source

Conference Talk. Bertelsmann Policy Brief 04.2019 [PDF]

open access: yes, 2019
Commission President Ursula von der Leyen has announced a two-year Conference on the Future of Europe. Even citizens ought to participate. But how? In order to make participatory democracy a reality, it is essential to avoid only paying lip-service to ...
Hierlemann, Dominik
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Downsian competition with participatory democracy [PDF]

open access: yes, 2013
We study a scenario where elections are held and two parties, a traditional downsian party and a party implementing Participatory Democracy, compete to win elections.
Puy Segura, Socorro   +1 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Efficient Mechanisms of Cooperation between Non-Governmental Organisations and Public Authorities

open access: yesActa Universitatis Danubius: Administratio, 2015
This paper aims to present to the wide public a success story concerning the efficient cooperation between the civil society as a whole (citizens, NGOs, stake holders) and public administration authorities.
Rucsandra FILLOREANU   +2 more
doaj  

Participação como representação: o impacto das conferências nacionais de políticas públicas no Congresso Nacional

open access: yesDados: Revista de Ciências Sociais, 2011
The relationship between representative democracy and participatory and deliberative experiences is not trivial. Those who endorse the discourse of a crisis in political representation sometimes defend participatory and deliberative modalities of ...
Thamy Pogrebinschi, Fabiano Santos
doaj   +1 more source

From Political Clientelism to Participatory Democracy

open access: yesEngagement: Jurnal Pengabdian Kepada Masyarakat, 2022
The Act of Village has given many opportunities for villages in Indonesia to generate innovation in the local contexts. The governance for village development creates a new way to develop the rural area through visionary leadership innovation. This study
Abdur Rozaki
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

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