Results 31 to 40 of about 16,953 (302)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Doctors of Democracy: Self-Image and Democratic Values of Participatory Practitioners
Journal of Deliberative Democracy, 2023 Against the backdrop of a perceived crisis of democracy, governments around the globe have extended citizens’ opportunities for public participation. Due to the increasing routinization of participatory processes, a vibrant participation industry has ...
Dennis Friess, Nina Katharina Herff
doaj +2 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Participatory budgeting - a neighbourhood manager's perspective [PDF]
, 2010 This study reports the impact of the requirement to consult with citizens on budgeting decisions through Participatory Budgeting. The Duty to Involve agenda was imposed as a legal duty in April 2009 on all local authorities set out by the Labour ...
Naylor, Sara
core
Dados: Revista de Ciências Sociais, 2011 The relationship between representative democracy and participatory and deliberative experiences is not trivial. Those who endorse the discourse of a crisis in political representation sometimes defend participatory and deliberative modalities of ...
Thamy Pogrebinschi, Fabiano Santos
doaj +1 more source
From Political Clientelism to Participatory Democracy
Engagement: Jurnal Pengabdian Kepada Masyarakat, 2022 The Act of Village has given many opportunities for villages in Indonesia to generate innovation in the local contexts. The governance for village development creates a new way to develop the rural area through visionary leadership innovation. This study
Abdur Rozaki
doaj +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
, 2023 Magister Administrationis - MAdminThe study investigates whether residents in informal settlements in Cape Town use social media technology to deepen democracy.
Cuphe, Madoda Floyd
core
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source