Results 51 to 60 of about 1,386,178 (330)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Participatory budgeting like new element in regional and public economy [PDF]

open access: yes, 2006
Participatory Budgeting (ve zkratce PB; překlad do češtiny: správa věcí veřejných v rukou veřejnosti) je nástroj, který umožňuje realizovat dvě základní výzvy: kontinuitu v demokracii a rozvoj aktivního podílu občanů na správě věcí veřejných.
Stejskal, Jan
core   +1 more source

Los modelos de democracia participativa en el constitucionalismo andino: los casos de Venezuela y Bolivia

open access: yesRevista Vasca de Administración Pública, 2017
The Constitutions approved during the last two decades in the Andean zone of Latin America have created a constitutional form of their own, with elements different from traditional constitutionalism.
Albert Noguera Fernández
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Participatory Democracy in Reforming the Way of Political Organization of Contemporary Society - European Models

open access: yesІсторико-політичні проблеми сучасного світу, 2018
This article analyzes the phenomenon of participatory democracy and the impact of community norms on the process of democratization in the context of reforming the way of political organization of contemporary society.
Валентина Урсу
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Reforming the Relationship between the State and Civil Society in Latin America

open access: yesLatin American Research Review, 2018
This essay reviews the following works: Enhancing Democracy: Public Policies and Citizen Participation in Chile. By Gonzalo Delamaza. New York: Berghahn Books, 2015. Pp. vi + 296. $99.00 hardcover. ISBN: 9781782385462. The Politics of Local Participatory
Maureen Donaghy
doaj   +1 more source

The Doctors of Democracy: Self-Image and Democratic Values of Participatory Practitioners

open access: yesJournal of Deliberative Democracy, 2023
Against the backdrop of a perceived crisis of democracy, governments around the globe have extended citizens’ opportunities for public participation. Due to the increasing routinization of participatory processes, a vibrant participation industry has ...
Dennis Friess, Nina Katharina Herff
doaj   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Participação como representação: o impacto das conferências nacionais de políticas públicas no Congresso Nacional

open access: yesDados: Revista de Ciências Sociais, 2011
The relationship between representative democracy and participatory and deliberative experiences is not trivial. Those who endorse the discourse of a crisis in political representation sometimes defend participatory and deliberative modalities of ...
Thamy Pogrebinschi, Fabiano Santos
doaj   +1 more source

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