Results 111 to 120 of about 1,594,468 (340)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Evaluation based on critical systems heuristics [PDF]

, 2007
Introduction: Critical systems heuristics (CSH) draws on the substantive work and philosophy of C. West Churchman, a systems engineer who, along with Russell Ackoff during the 1950s and 1960s, defined operations research in the United States.
Reynolds, Martin
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Integrating participatory GIS into spatial planning regulation: The case of Merauke District, Papua, Indonesia

International Journal of the Commons, 2018
In many cases, government institutions lack to consider community areas as a part of their traditional land use in spatial planning policy. The results of numerous investigations into participatory mapping have been insufficiently adopted by Spatial ...
Barano Siswa Sulistyawan, Pita A Verweij, Rene G.A. Boot, Bekti Purwanti, Wika Rumbiak, Marthinus C Wattimena, Paschalina Rahawarin, Gemasakti Adzan   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Factors affecting cultural ecosystem services use in Vilnius (Lithuania): A participatory mapping survey approach. [PDF]

Heliyon, 2023
Pinto LV, Inácio M, Bogdzevič K, Kalinauskas M, Gomes E, Pereira P.   +5 more
europepmc   +1 more source

Participatory Ecosystem Management Planning at Tuzla Lake (Turkey) Using Fuzzy Cognitive Mapping

, 2005
A participatory environmental management plan was prepared for Tuzla Lake, Turkey. Fuzzy cognitive mapping approach was used to obtain stakeholder views and desires.
Akdogan, Asuman, Celik, Filiz Dadaser, Ozesmi, Uygar   +2 more
core  

Mapping intangibilities in creative tourism territories through tangible objects: a methodological approach for developing creative tourism offers [PDF]

, 2019
What can people express about their places through the objects that they valorise and link to their territory? Can objects create narratives about a place's identity and collect significant cultural information that locate people in their places?
Cabeça, Sónia Moreira, Gonçalves, Alexandra, Marques, Joao Filipe, Tavares, Mirian   +3 more
core   +1 more source

Questioning the practice of participation: Critical reflections on participatory mapping as a research tool

Applied Geography, 2023
M. Laituri, M. Luizza, Jamie D. Hoover, A. M. Allegretti   +3 more
semanticscholar   +1 more source