Results 121 to 130 of about 1,594,468 (340)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
How to overcome the governance challenges of implementing NREGA [PDF]
Large-scale social safety net programs such as India s National Rural Employment Guarantee Act (NREGA) are difficult to implement due to governance challenges related to elite capture, leakages, and corruption.
Birner, Regina +5 more
core
Land, 2017 Participatory mapping of local land use as the basis for planning and decision-making has become widespread around the globe. However, still relatively little is known about the conceptual underpinnings of geographic information produced through ...
Flurina M. Wartmann, Ross S. Purves
doaj +1 more source
A learning-based algorithm for generation of synthetic participatory mapping data in 2D and 3D. [PDF]
MethodsX, 2022 Hasanzadeh K, Fagerholm N.
europepmc +1 more source
Capturing and representing deliberation in participatory planning practices [PDF]
, 2010 In this paper we argue for the importance of capturing and representing deliberation in participatory planning practices. We discuss the concept of deliberation in planning theory, and argue for a paradigm that puts deliberation at the centre of public ...
Buckingham Shum, Simon, De Liddo, Anna
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Making sense of assets: Community asset mapping and related approaches for cultivating capacities [PDF]
, 2016 This working paper critically reviews some main aspects from asset based approaches highlights key strengths and weaknesses for future research/development.
Alevizou, Giota +2 more
core
Participatory mass observation and citizen science. [PDF]
, 2011 The authors outline and reflect upon a new research agenda on participatory mass observation and citizen science as an introduction to the 3 project outlines in this special section of ...
Ellis, Rebecca +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source