Results 71 to 80 of about 15,380 (259)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Integrating participatory GIS into spatial planning regulation: The case of Merauke District, Papua, Indonesia

International Journal of the Commons, 2018
In many cases, government institutions lack to consider community areas as a part of their traditional land use in spatial planning policy. The results of numerous investigations into participatory mapping have been insufficiently adopted by Spatial ...
Barano Siswa Sulistyawan, Pita A Verweij, Rene G.A. Boot, Bekti Purwanti, Wika Rumbiak, Marthinus C Wattimena, Paschalina Rahawarin, Gemasakti Adzan   +7 more
doaj   +1 more source

Factors affecting cultural ecosystem services use in Vilnius (Lithuania): A participatory mapping survey approach. [PDF]

Heliyon, 2023
Pinto LV, Inácio M, Bogdzevič K, Kalinauskas M, Gomes E, Pereira P.   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Paper2GIS: improving accessibility without limiting analytical potential in Participatory Mapping. [PDF]

J Geogr Syst, 2023
Denwood T, Huck JJ, Lindley S.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Participatory Mapping as a Tool for Social Justice and Mobilization in Brazilian Informal Settlements

Media and Communication
Participatory mapping’s main aim is to represent the community’s voice. It stimulates a powerful social mobilization that provides support for better and more efficient urban policies and social inclusion of marginalized populations, especially in Global
Carolina Monteiro de Carvalho
doaj   +1 more source

A learning-based algorithm for generation of synthetic participatory mapping data in 2D and 3D. [PDF]

MethodsX, 2022
Hasanzadeh K, Fagerholm N.
europepmc   +1 more source