Results 81 to 90 of about 15,380 (259)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

What’s (Not) on the Map: Landscape Features from Participatory Sketch Mapping Differ from Local Categories Used in Language

Land, 2017
Participatory mapping of local land use as the basis for planning and decision-making has become widespread around the globe. However, still relatively little is known about the conceptual underpinnings of geographic information produced through ...
Flurina M. Wartmann, Ross S. Purves
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Participatory mapping identifies risk areas and environmental predictors of endemic anthrax in rural Africa. [PDF]

Sci Rep, 2022
Aminu OR, Forde TL, Ekwem D, Johnson P, Nelli L, Mmbaga BT, Mshanga D, Shand M, Shirima G, Walsh M, Zadoks RN, Biek R, Lembo T.   +12 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Seeking Refuge in South Africa: Navigating Power, Healing, and Co‐Creation in Body‐Mapping Processes

Social Inclusion
This article refines the participatory body‐mapping process drawing insights from a preparatory workshop in South Africa, the country of origin of the method.
Syeda Sidra Idrees, Karin Hannes, Marisa de Andrade   +2 more
doaj   +1 more source

Participatory mapping to address neighborhood level data deficiencies for food security assessment in Southeastern Virginia, USA. [PDF]

Int J Health Geogr, 2022
Hutton NS, McLeod G, Allen TR, Davis C, Garnand A, Richter H, Chavan PP, Hoglund L, Comess J, Herman M, Martin B, Romero C.   +11 more
europepmc   +1 more source

Many, many maps: Empowerment and online participatory mapping

First Monday, 2007
The convergence of public participatory mapping and cybertography is having far-reaching impacts through a variety of creative applications. This paper presents three different types of Internet mapping applications — Google Earth and Google Map API, Common Census, and a design exercise in Second Life — with a public participatory geographic ...
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Participatory Mapping with Herders in a Climate Adaptation Research Project. [PDF]

Pract Anthropol, 2021
Nébié EKI, West CT, Crane TA.
europepmc   +1 more source