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The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

A systematic review of participatory research involving forensic mental health patients. [PDF]

BMC Psychiatry
Ferra F, Walde P, Daum M, Teipel S, Drewelow E, Biernetzky O, Völlm B.   +6 more
europepmc   +1 more source

Developing and applying the 'Participatory Research to Action Framework' for meaningful engagement of experts-by-experience in applied health services research: a case study approach. [PDF]

Res Involv Engagem
L Giosa J, Evans C, Cardozo V, Holyoke P.   +3 more
europepmc   +1 more source

Promoting Mental Health, Physical Activity, and Healthy and Sustainable Dietary Behavior Among Practical Education Students in the Netherlands: Protocol for a Multiphase Participatory Research Study.

JMIR Res Protoc
van Uden D, Wagemakers A, Peeters M, Kleinjan M, Verkooijen K.   +4 more
europepmc   +1 more source

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Participatory modelling: Participatory research methods for sustainability ‐ toolkit #6

GAIA - Ecological Perspectives for Science and Society, 2023
Sustainability challenges require the integration of diverse knowledge types for understanding and managing social-ecological systems. Participatory modelling includes the active involvement of stakeholders in the design, development, and use of models addressing sustainability and natural resource management challenges.
Romina Martin, Udita Sanga
openaire   +1 more source

Participatory Methods for Water Resources Planning [PDF]

Environment and Planning C: Government and Policy, 2006
The Water Framework Directive institutionalises participatory processes in river basin planning across the European Union. This paper reports on three case studies from southern Europe where conflicts over water exist. In each a different method for participation was experimentally employed: scenario workshops, mediated modelling, and social ...
Giorgos Kallis, Nuno Videira, Paula Antunes, Ângela Guimarães Pereira, Clive L Spash, Harry Coccossis, Serafin Corral Quintana, Leandro del Moral, Dionisia Hatzilacou, Gonçalo Lobo, Alexandra Mexa, Pilar Paneque, Belen Pedregal Mateos, Rui Santos   +13 more
openaire   +1 more source