Results 71 to 80 of about 11,392 (259)

Learning about social-ecological trade-offs

open access: yesEcology and Society, 2017
Trade-offs are manifestations of the complex dynamics in interdependent social-ecological systems. Addressing trade-offs involves challenges of perception due to the dynamics of interdependence.
Diego Galafassi   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Centering and collaborating with community knowledge systems: piloting a novel participatory modeling approach. [PDF]

open access: yesInt J Equity Health, 2023
Shaikh Y   +7 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Participatory Modelling

open access: yes, 2010
[Departement_IRSTEA]Eaux [TR1_IRSTEA]GEUSI ; International ...
Sendzimir, J.   +5 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ARDI: A Co-construction Method for Participatory Modeling in Natural Resources Management

open access: yesEcology and Society, 2011
The outcomes of a series of tests of the ARDI (Actors, Resources, Dynamics, and Interactions) method in complex cases or conflict-ridden situations is presented.
Michel Etienne   +2 more
doaj   +1 more source

Mapping the Complexity of Suicide by Combining Participatory Modeling and Network Science. [PDF]

open access: yesProc IEEE ACM Int Conf Adv Soc Netw Anal Min, 2021
Giabbanelli PJ   +7 more
europepmc   +1 more source

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