Results 71 to 80 of about 5,843,235 (252)

Introduction: Making Sense of Pain

, 2011
Given that making sense of pain will continue to accrue progressive controversies as much as qualified consensus, we are indebted to those who over time have added to our understanding of pain.
Fernandez-Goldborough, Jane L.
core   +1 more source

Becoming activists: how young athletes use visual tools for civic action and meaning-making within participatory research

Frontiers in Political Science
How can participatory research, combined with visual methods, enable young people to grow as engaged citizens in their communities? This article introduces an innovative methodological design that draws on a Youth Participatory Action Research (YPAR ...
Daniel Vieira, Daniel Vieira, Teresa Silva Dias, Teresa Silva Dias, Marta Sampaio, Marta Sampaio, Sofia Castanheira Pais, Sofia Castanheira Pais, Norberto Ribeiro, Norberto Ribeiro, Cosmin Nada, Cosmin Nada, Cosmin Nada, Carla Malafaia, Carla Malafaia   +14 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Participatory Monitoring and Management Partnership

, 2015
The Participatory Monitoring and Management Partnership  (PMMP) is an international collaborative network for local leaders and communities working with participatory monitoring and management of natural resources. The Partnership seeks to transform
Participatory Monitoring and Management Partnership
core  

Cognitive Networks: Interactivity, Intersubjectivity, and Synergy

Філософія освіти, 2017
Some properties of cognitive networks are discussed in the article in the context of the modern achievements of the network science. It is the study in network structures and their surprising properties that gives a new impetus to the development of the ...
Helena Knyazeva
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Acting as Participatory Sense Making

, 2018
I artikeln undersöker jag skådespelarens arbete som ”förkroppsligad subjunktivitet”, dvs från aspekten ”vad skulle jag göra om jag var i rollfigurens situation”? Jag diskuterar detta i relation till en enaktiv teori om social interaktion, nämligen den om
Rynell, Erik
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source