Results 51 to 60 of about 512,842 (292)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Particle-in-Cell simulations of electron spin effects in plasmas

, 2012
We have here developed a particle-in-cell code accounting for the magnetic dipole force and for the magnetization currents associated with the electron spin.
Brodin, G., Holkundkar, A., Marklund, M.
core   +1 more source

Collimated γ-flash emission along the target surface irradiated by a laser at non-grazing incidence

New Journal of Physics
The interaction of a high-power laser with a solid target provides ways to produce beams of γ -photons. For normal incidence of the laser on the target the beams usually appear in a form of two lobes, which are symmetric with respect to the laser ...
M Matys, P Hadjisolomou, R Shaisultanov, P Valenta, M Lamač, T M Jeong, J P Thistlewood, C P Ridgers, A S Pirozhkov, S V Bulanov   +9 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Bubble regime of plasma wakefield in 2D and 3D geometries

, 2018
Considering the popularity of two-dimensional particle-in-cell simulations, a 2D model of plasma wakefield in the strongly nonlinear (bubble) regime in transversely non-uniform plasma is developed.
Golovanov, A. A., Kostyukov, I. Yu.
core   +1 more source

Poloidally asymmetric potential formation on plasma boundary in axisymmetric magnetic field

Frontiers in Physics
To study the symmetry of electrical potential, we model plasma transport in the edge region of a toroidal device with two spatial dimensions (2D) and three coordinates for velocities (3V) using a Particle-In-Cell (PIC) code.
Trang Le, Trang Le, Yasuhiro Suzuki, Hiroaki Ohtani, Hiroaki Ohtani, Hiroki Hasegawa, Hiroki Hasegawa, Toseo Moritaka, Toseo Moritaka   +8 more
doaj   +1 more source

A high‐order accurate particle‐in‐cell method [PDF]

International Journal for Numerical Methods in Engineering, 2012
SUMMARYWe propose the use of high‐order weighted essentially non‐oscillatory interpolation and moving‐least‐squares approximation schemes alongside high‐order time integration to enable high‐order accurate particle‐in‐cell methods. The key insight is to view the unstructured set of particles as the underlying representation of the continuous fields ...
Edwards, Essex, Bridson, Robert
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Ab-initio pulsar magnetosphere: the role of general relativity

, 2015
It has recently been demonstrated that self-consistent particle-in-cell simulations of low-obliquity pulsar magnetospheres in flat spacetime show weak particle acceleration and no pair production near the poles.
Cerutti, Benoît, Philippov, Alexander A., Spitkovsky, Anatoly, Tchekhovskoy, Alexander   +3 more
core   +1 more source