Results 41 to 50 of about 67,903 (312)

Particle-in-cell simulations for fast ignition

Journal of Physics: Conference Series, 2008
The hole-boring scheme in fast ignition is studied via largee-scale, two-dimensional particle-in-cell simulations in two steps. First, laser channeling in millimeter-scale underdense plasmas is simulated. The results show a highly nonlinear and dynamic process involving longitudinal plasma buildup, laser hosing, channel bifurcation and self-correction,
C Ren, J Tonge, G Li, F Fiuza, R A Fonseca, J May, W B Mori, L O Silva, T L Wang, R Yan   +9 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Laguerre–Gaussian pulses for spin-polarized ion beam acceleration

High Power Laser Science and Engineering
Polarized particle sources have a plethora of applications, ranging from deep-inelastic scattering to nuclear fusion. One crucial challenge in laser–plasma interaction is maintaining the initial polarization of the target.
Lars Reichwein, Tong-Pu Yu, Alexander Pukhov, Markus Büscher   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Particle-in-cell simulations of a lens on an f-plane [PDF]

Nonlinear Processes in Geophysics, 1997
A particle-in-cell ansatz for solving the Euler equations in a rotating frame is described. The approach is ideally suited for 'layered' models of flows with sharp density and velocity fronts.
A. D. Kirwan, Jr., C. E. Grosch, C. E. Grosch, J. J. Holdzkom II.   +3 more
doaj  

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Particle-in-cell beam dynamics simulations with a wavelet-based Poisson solver

Physical Review Special Topics. Accelerators and Beams, 2007
We report on a successful implementation of a three-dimensional wavelet-based solver for the Poisson equation with Dirichlet boundary conditions, optimized for use in particle-in-cell (PIC) simulations.
Balša Terzić, Ilya V. Pogorelov, Courtlandt L. Bohn   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Particle-in-Cell Simulations of Quantum Plasmas

Room-temperature metals and semi-metals which consist of a gas of bound electrons in a near-continuum band structure can be classified as cold quantum plasmas. This insight suggests that Particle-in-Cell (PIC) simulations, traditionally used for modeling classical plasmas, may be adapted for the next generation of nanoscopic simulations in photonics ...
Ngirmang, Gregory K., Do, Hue T. B., Liu, Guangxin, Bosman, Michel, Wu, Lin   +4 more
openaire   +2 more sources