Results 61 to 70 of about 909,214 (267)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Глаголи с елемента “си” / “sobie” в българския и в полския език
Zeszyty Cyrylo-Metodiańskie, 2017 Verbs with the Element „си” / „sobie” in Bulgarian and Polish Languages: The paper examines the phenomenon of reflexive personal pronouns for the dative case, used with verbs in several Slavic languages.
Savova, Dimka
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Masked particle modeling on sets: towards self-supervised high energy physics foundation models
Machine Learning: Science and TechnologyWe propose masked particle modeling (MPM) as a self-supervised method for learning generic, transferable, and reusable representations on unordered sets of inputs for use in high energy physics (HEP) scientific data.
Tobias Golling +6 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Functioning of the word combination “da vsio ravno” in modern Russian language
Studia HumanitatisThe article examines the use of the word combination “da vsio ravno” by modern native speakers of Russian using examples from the Russian National Corpus. This combination includes the polyfunctional word “da”, which can act as an adversative conjunction
Krylova Maria Nikolaevna
doaj
A Comparative Statistical Analysis of Two Brake Emission Test Cycles
AtmosphereNon-exhaust emissions represent a growing share of traffic-related particulate matter and are increasingly addressed by regulatory frameworks. This study presents a comparison of two brake emission test cycles, the California Brake Dynamometer Cycle ...
Sampsa Martikainen +6 more
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Tribology in Natural Sand Dust Environment
Tribology Online, 2008 The tribological problem in natural sand dust environment was proposed and an equipment for simulating the natural sand dust environment based on Multi-Venturi structure was introduced for studying the tribological problem.
Dongfeng Diao, Tonghai Wu
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source