Results 111 to 120 of about 43,251,177 (344)

A particle-resolved heat-particle-fluid coupling model by DEM-IMB-LBM

Journal of Rock Mechanics and Geotechnical Engineering
Multifield coupling is frequently encountered and also an active area of research in geotechnical engineering. In this work, a particle-resolved direct numerical simulation (PR-DNS) technique is extended to simulate particle-fluid interaction problems ...
Ming Xia, Jinlong Fu, Y.T. Feng, Fengqiang Gong, Jin Yu   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

An integrated particle model for fluid–particle–structure interaction problems with free-surface flow and structural failure

, 2018
Discrete Element Method (DEM) and Smoothed Particles Hydrodynamics (SPH) are integrated to investigate the macroscopic dynamics of fluid–particle–structure interaction (FPSI) problems. With SPH the fluid phase is represented by a set of particle elements
Ke Wu, Dong-Min Yang, N. Wright, Amirul Khan   +3 more
semanticscholar   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Particle Physics Models of Inflation [PDF]

, 2007
Based on a talk given at the 22nd IAP Colloquium, ``Inflation +25'', Paris, June 2006 Curve omitted from final ...
openaire   +2 more sources

A rao-blackwellized particle filter for INS/GPS integration [PDF]

, 2004
The localization performance of a navigation system can be improved by coupling different types of sensors. This paper focuses on INS-GPS integration.
Giremus, Audrey, Doucet, Arnaud, Calmettes, Vincent, Tourneret, Jean-Yves, A. Doucet, A. Giremus, V. Calmettes, J.-Y. Tourneret   +7 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A novel particle–particle and particle–wall collision model for superellipsoidal particles

Computational Particle Mechanics
Abstract.
Jana Wedel, Mitja Štrakl, Matjaž Hriberšek, Paul Steinmann, Jure Ravnik   +4 more
openaire   +4 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source