Results 111 to 120 of about 542,620 (267)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A New Motion Model Selection Approach for Multi-Model Particle Filters [PDF]
Radioengineering, 2019 One of the important factors in real-time tracking of the moving radar targets is the speed of the algorithm. In the multi-model particle filters (MMPFs) which is frequently preferred tracking of such targets, the numbers of particles and motion models ...
M. B. Ucar, D. Yilmaz
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
A Geometric Model For Extended Particles
, 2012 Here we combine the ideas of a quantum functional theory intended to describe intrinsically extended particles with those of a geometro-stochastic one describing stochastically extended particles. The main ingredients of the former are a physical wave $u$ replacing the point ${\bf x}$ and a functional wave $X[u,t]$ replacing the probability wave ...
Smida, Abdallah +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Elastoplastic constitutive model for granular materials considering meso-particle damage
Yantu gongcheng xuebaoEstablishing a constitutive model for granular materials that accounts for particle shape and breakage mechanisms has been crucial for calculating the mechanical stability of earth-rock dam projects. Initially, through the triaxial compression tests, the
WANG Xiaochan 1 , LAN Hengxing 1, 2, 3, LIU Shijie 1, SUN Weifeng 1
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Extended Particle Model of Elementary Particles [PDF]
Progress of Theoretical Physics Supplement, 1968 Osamu Hara, Tetsuo Gotō
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A physical particle model of morphogenesis [PDF]
, 2003 This paper describes an evolutionary process which produces dynamic biologic-like patterns. Simulation and visualization of the development of cell populations has many applications. For example, developmental biology and computer graphics. Physically-based particle models are efficient to simulate the dynamical behavior of real life objects.
Boulenguez, Pierre, Luciani, Annie
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