Results 81 to 90 of about 542,620 (267)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Advances in Mechanical Engineering, 2015 In this article, three stochastic separated flow models were applied to predict the dispersion of inertial fuel particles in the supersonic turbulent flows.
Bing Wang, Zhaoxin Ren, Huiqiang Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Model for Independent Particle Motion
, 2022 38 pages, 14 figures, Contribution to the "Handbook of Nuclear Physics", Springer Nature, 2022, Eds. I. Tanihata, H. Toki and T.
openaire +2 more sources
Particle modelling of an elastic arch
Applied Mathematical Modelling, 1985 A new particle-type of modelling has been developed for the simulation of phenomena related to the bending of an elastic arch. Application is made to the simulation of snap-through inversion and to the simulation of unstable equilibrium modes. Computer examples are described and discussed.
D. Greenspan, Casulli, Vincenzo
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A particle model of fluid sloshing
Mathematical and Computer Modelling, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
The standard model of particle physics
Reviews of Modern Physics, 1999 25 pages, 17 figures; accepted for publication in Rev. Mod. Physics (APS centenary issue)
Gaillard, Mary K. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source