Results 41 to 50 of about 5,905,435 (301)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Effect of Particle Size and Constraint Conditions on Single Particle Strength of Carbonate Sand
Sensors, 2022 Carbonate sand is often encountered and utilized as construction material in offshore engineering projects. Carbonate sand particles, which are porous and angular, are found to be highly crushable under high stress conditions, whereas the mechanisms and ...
Yong He, Guojun Cai, Lei Gao, Huan He
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Water, 2021 Many particulate pollutants in the environment exist in non-spherical shape, but the influences of particle shape on pollutant migration and removal in groundwater systems are not well-understood.
Ke Li, Huilian Ma
doaj +1 more source
Shape matters: Competing mechanisms of particle shape segregation
Physical Review E, 2022 It is well-known that granular mixtures that differ in size or shape segregate when sheared. In the past, two mechanisms have been proposed to describe this effect, and it is unclear if both exist. To settle this question, we consider a bidisperse mixture of spheroids of equal volume in a rotating drum, where the two mechanisms are predicted to act in ...
D. Hernández-Delfin +4 more
openaire +5 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
KONA Powder and Particle Journal, 2014 A wet micro-feeder that utilizes ultrasonic wave force was designed and constructed to feed small particles into a container of wet particulate materials. The particle discharge characteristics from a nozzle with the
Kenichi Yamamoto +4 more
doaj +1 more source
Molecular Dynamics Simulation of Zener Pinning by Differently Shaped and Oriented Particles
Frontiers in Materials, 2021 Zener pinning between a curved Cu grain boundary (GB) and a differently shaped and oriented Ag particle has been simulated via molecular dynamics. The computed magnitudes of the maximum pinning force agreed with theoretical predictions only when the ...
Yi Li +3 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source