Results 61 to 70 of about 3,316,013 (300)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Combining experiment and prediction to explore surface chemistry and dissolution
IUCrJA crystal structure is often an integral component in the development of a new pharmaceutical product, and these structures are frequently used to understand, assess and often predict both the manufacturing and in vivo behaviour of these compounds ...
Andrew G. P. Maloney
doaj +1 more source
Performance Parameters and Characterizations of Nanocrystals: A Brief Review
Pharmaceutics, 2016 Poor bioavailability of drugs associated with their poor solubility limits the clinical effectiveness of almost 40% of the newly discovered drug moieties.
Manasi M. Chogale +2 more
doaj +1 more source
Geotechnics, 2023 The analysis of sands, and the foundation systems with which they interact, are largely dependent on macroscale behavioral parameters that represent the aggregated response of several microscale characteristics. This research paper examines the influence
Anthony Tessari, Mark Muszynski
doaj +1 more source
Shape-Directed Microspinners Powered by Ultrasound
, 2018 The propulsion of micro- and nanoparticles using ultrasound is an attractive strategy for the remote manipulation of colloidal matter using biocompatible energy inputs. However, the physical mechanisms underlying acoustic propulsion are poorly understood,
Syeda Sabrina (4926688) +20 more
core +1 more source
Values of empirical shape factor for different particle shapes.
, 2021 Values of empirical shape factor for different particle shapes.
Saba Javaid (11539828) +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Applied SciencesParticle shape is a critical factor governing the macroscopic behavior of granular materials. While the Discrete Element Method (DEM) has proven to be a powerful tool for modeling these materials, the accurate representation of particles with realistic ...
Pei Zhang +5 more
doaj +1 more source
Studia Geotechnica et Mechanica, 2015 The mechanical performance of underground flexible structures such as buried pipes or culverts made of plastics depend not only on the properties of the structure, but also on the material surrounding it.
Szarf Krzysztof +2 more
doaj +1 more source
Discrete element modeling of non-spherical particles using a spherical shape
REM: International Engineering Journal, 2020 Real non-spherical particles can be modeled using the Discrete Element Method (DEM) with sphere clusters, superquadrics, or polyhedral particles. However, in applications involving a considerable number of particles, the analysis can become impracticable.
Elias Gomes Santos +5 more
doaj +1 more source