Results 91 to 100 of about 5,905,435 (301)

Shape of Small Particles [PDF]

open access: yesNature, 1964
I REGRET that the index 2 was omitted from one of the β's in the denominator of equation (19) in my article published in Nature under the above title1; this was due to an error in the analysis which escaped me and was later detected by Mr. J. Cartwright of the Safety in Mines Research Establishment when applying the method to coal dust.
openaire   +1 more source

The impact of particle shape on fall velocity: Implications for volcanic ash dispersion modelling

open access: yesJournal of Volcanology and Geothermal Research, 2018
Modelling atmospheric volcanic ash dispersion is a critical tool in mitigating the impact of large explosive eruptions; it is also useful for understanding and reconstructing past events.
J. Saxby   +4 more
semanticscholar   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Lunar regolith simulations with discrete element method based on Chang'E-5 mission's lunar soil particle morphology

open access: yesYantu gongcheng xuebao
To align with the current strategic planning of "survey, mining, and development" in China's lunar exploration mission, and to obtain more accurate physical and mechanical properties of lunar regolith, this study focuses on the influences of lunar ...
WANG Siyuan 1, , JIANG Mingjing 2, 3, 4
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Internal Friction Angle of Metal Powders

open access: yesMetals, 2018
Metal powders are components with multidisciplinary usage as their application is very broad. Their consistent characterization across all disciplines is important for ensuring repeatable and trouble-free processes.
Jiri Zegzulka   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Coupled Effects of Fines Content and Particle Shape on the Maximum Shear Modulus of Gap-Graded Soils: A DEM Investigation

open access: yesBuildings
The maximum shear modulus (Gmax) of soils is a critical parameter in geotechnical design and advanced constitutive modeling. While the effects of fines content (FC) and particle shape on Gmax have been studied extensively, their collective influence on ...
Yuyang Tian   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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