Results 111 to 120 of about 246,503 (260)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Advancements in Understanding Interface Friction: A Combined Experimental and Machine Learning Approach Using Multiple Linear and Random Forest Regressions

open access: yesGeotechnics
The interface friction between granular materials and continuum surfaces is fundamental in civil engineering, especially in geotechnical projects where sand of varying sizes and shapes contacts surfaces with different roughness and hardness.
Firas Daghistani, Hossam Abuel-Naga
doaj   +1 more source

Impact of Particle Shape and Surface Group on Membrane Fouling. [PDF]

open access: yesMembranes (Basel), 2022
Tanis-Kanbur MB   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The effect of particle shape on discharge and clogging. [PDF]

open access: yesSci Rep, 2021
Hafez A   +5 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Application of Multivariate Tromp Functions for Evaluating the Joint Impact of Particle Size, Shape and Wettability on the Separation of Ultrafine Particles via Flotation

open access: yesPowders
Froth flotation predominantly separates particles according to their differences in wettability. However, other particle properties such as size, shape or density significantly influence the separation outcome as well.
Johanna Sygusch   +5 more
doaj   +1 more source

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