Results 111 to 120 of about 3,316,013 (300)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Effect of particle shape on the dynamic deformation characteristics of artificially simulated rockfill material

open access: yesShuili Shuiyun Gongcheng Xuebao
Rockfill material, as the primary construction material for earth-rock dams, exhibits dynamic deformation characteristics under seismic action that are influenced by particle shape, gradation, and relative density.
YANG Gui, LIU Yu, TANG Chenjing
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Shear Response of Sand Under Prescribed Post-Crushing Scenarios Considering Fractal Change in Particle Size and Shape: A DEM Study

open access: yesFractal and Fractional
Particle crushing changes both particle size distribution and particle shape, which significantly affects the mechanical behavior of sand. This study uses a multi-scale discrete element method to investigate the direct-shear response of sand under ...
Abdulmuttalip Ari, Felix Okonta
doaj   +1 more source

ELECTRODEPOSITION OF COPPER POWDER FROM MIXTURE SULPHATE –CHLORIDE ACIDIC SOLUTION

open access: yesIraqi Journal for Mechanical and Materials Engineering, 2018
This paper studies the preparation of Copper powder from Copper Sulphate aqueous solution(CuSO4.5H2O), sulfuric acid (H2SO4) and copper chloride (CuCl2.2H2O)by using the process of electro-deposition.
Sundus A Jasim
doaj   +1 more source

Effect of Particle Shape on the Flow of an Hourglass

open access: yesPhysical Review Letters
The flow rate of a granulate out of a cylindrical container is studied as a function of particle shape for flat and elongated ellipsoids experimentally and numerically. We find a nonmonotonic dependence of the flow rate on the grain aspect ratio a/b.
Bo Fan   +3 more
openaire   +3 more sources

Gravity optimised particle filter for hand tracking [PDF]

open access: yes, 2014
This paper presents a gravity optimised particle filter (GOPF) where the magnitude of the gravitational force for every particle is proportional to its weight. GOPF attracts nearby particles and replicates new particles as if moving the particles towards
Tjahjadi, Tardi   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Shape-directed rotation of homogeneous micromotors via catalytic self-electrophoresis

open access: yesNature Communications, 2019
The pursuit of chemically-powered colloidal machines requires individual components that perform different motions within a common environment. Such motions can be tailored by controlling the shape and/or composition of catalytic microparticles; however,
Ada M. Brooks   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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