Results 131 to 140 of about 5,905,435 (301)

Effect of the particle shape on the shear mechanical behavior of coral sand

Materials Research Express
Coral sand particles exhibit a wide range of shapes, which can be divided into four shapes, e.g., blocky, dendritic and rodlike, flaky, and shell debris. The particle shape of these mixtures is defined by the sphericity, concavity, aspect ratio, flatness
Xin Zhang, Linjian Ma, Jiewei Ke, Zhiqiang Yan, Zheyan Feng, Limingxin Zong   +5 more
doaj   +1 more source

The effect of particle shape on the deformation and stress reduction of a gravel soil due to wetting. [PDF]

Sci Rep, 2021
Mahinroosta R, Oshtaghi V.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Particle Shape Control by Rounding Irregular Shaped Particles-Effects of Particle Shapes on Fluidity of Pulverized Coal in CWM and Fly-ash Particles.

Journal of the Society of Powder Technology, Japan, 1998
Tetsuo ONO, Yoshiyuki YAMASAKI
openaire   +3 more sources

Analyzing the Effect of Particle Shape on Deformation Mechanism during Cutting Simulation of SiC P/Al Composites. [PDF]

Micromachines (Basel), 2021
Zhou J, Lin J, Lu M, Jing X, Jin Y, Song D.   +5 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Particle shape does not affect ingestion and egestion of microplastics by the freshwater shrimp Neocaridina palmata. [PDF]

Environ Sci Pollut Res Int, 2021
Klein K, Heß S, Nungeß S, Schulte-Oehlmann U, Oehlmann J.   +4 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Impact of Critical Material Attributes (CMAs)-Particle Shape on Miniature Pharmaceutical Unit Operations. [PDF]

AAPS PharmSciTech, 2021
Azad MA, Capellades G, Wang AB, Klee DM, Hammersmith G, Rapp K, Brancazio D, Myerson AS.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source