Results 141 to 150 of about 291,283 (307)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aspherical, Nano-Structured Drug Delivery System with Tunable Release and Clearance for Pulmonary Applications

Pharmaceutics
Addressing the challenge of efficient drug delivery to the lungs, a nano-structured, microparticulate carrier system with defined and customizable dimensions has been developed.
Tomas Pioch, Thorben Fischer, Marc Schneider   +2 more
doaj   +1 more source

Efficient solution of particle shape functions for the analysis of powder total scattering data. [PDF]

J Appl Crystallogr, 2022
Leonardi A, Neder R, Engel M.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Global Optimization by Particle Swarm Method:A Fortran Program

Programs that work very well in optimizing convex functions very often perform poorly when the problem has multiple local minima or maxima. They are often caught or trapped in the local minima/maxima.
Mishra, SK
core   +1 more source

Assembling Biocompatible Polymers on Gold Nanoparticles: Toward a Rational Design of Particle Shape by Molecular Dynamics. [PDF]

ACS Omega, 2022
Cappabianca R, De Angelis P, Cardellini A, Chiavazzo E, Asinari P.   +4 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Shape-optimized soft-hard tandem tracers for enhanced magnetic particle imaging

Magnetic Particle Imaging (MPI) is a leading molecular imaging technique with unmatched potential for disease diagnosis, offering high contrast and sensitivity without radiation.
Yang, Peng
core   +1 more source

Synthesis of Hydrophobic Nanosized Silicon Dioxide with a Spherical Particle Shape and Its Application in Fire-Extinguishing Powder Compositions Based on Struvite. [PDF]

Nanomaterials (Basel), 2023
Valtsifer IV, Huo Y, Zamashchikov VV, Shamsutdinov AS, Kondrashova NB, Sivtseva AV, Pyankova AV, Valtsifer VA.   +7 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source