Results 121 to 130 of about 3,016,111 (298)

REVIEW OF PARTICLE PHYSICS Particle Data Group [PDF]

, 2018
The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 2,873 new measurements from 758 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson ...
Tanabashi, M., Particle Data Group, Eerola, P., Törnqvist, N. A.   +3 more
core   +1 more source

Morphology-Controlled Single Rock Particle Breakage: A Finite-Discrete Element Method Study with Fractal Dimension Analysis

Fractal and Fractional
This study investigates the influence of particle morphology on two-dimensional (2D) single rock particle breakage using the combined finite-discrete element method (FDEM) coupled with fractal dimension analysis.
Ruidong Li, Shaoheng He, Haoran Jiang, Chengkai Xu, Ningyu Yang   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Shape Machine and Architecture Theory

, 2019
Presented as part of the Shape Machine Symposium on April 11, 2019 at 11:30 a.m. in theJohn & Joyce Caddell Building, Flex Space.Heather Ligler is an architect and design researcher interested in how generative and parametric design both provide a new ...
Ligler, Heather
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Coupled Effects of Fines Content and Particle Shape on the Maximum Shear Modulus of Gap-Graded Soils: A DEM Investigation

Buildings
The maximum shear modulus (Gmax) of soils is a critical parameter in geotechnical design and advanced constitutive modeling. While the effects of fines content (FC) and particle shape on Gmax have been studied extensively, their collective influence on ...
Yuyang Tian, Xuan Wang, Xingyang Liu, Xingxing Ai   +3 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Investigation of the Impact of Particle Shape on Pore Structures and Clogging Properties of Filter Layers

Applied Sciences
This study posits that soil particles in the filter layer are ellipsoidal. The effective pore radius of the filter material was calculated for various particle-shape parameters and distributions.
Wei-Kang Bai, Fa-Ning Dang, Wu-Wei Zhu, Yi Yao, Hai-Bin Xue, Jun Gao   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source