Results 81 to 90 of about 466,075 (310)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The relationship between gunshot-residue particle size and Boltzmann distribution
Forensic Sciences Research, 2020 Gunshot-residue (GSR) particles usually form spherical structures, have special dimensions, and a composition that consists of burned and partially unburned matter with a 0.5–50-µm diameter (sometimes larger).
İlker Kara
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Design and numerical simulation of the real-time particle charge and size analyser
, 2012 The electrostatic charge and size distribution of aerosol particles play a very important role in many industrial applications. Due to the complexity and the probabilistic nature of the different charging mechanisms often acting simultaneously, it is ...
Zhang, Lu
core
Approximation of the soil particle-size distribution curve using a NURBS curve
Soil particle-size distribution or soil texture presents one of the most important physical properties. There are various systems of the classification systems for soil particle-size fractions with different boundaries. Our effort was concentrated on the
Petr Polák +8 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Experimental investigation of ultra-fine particle size distribution near a busy road
, 2004 In this paper, evolution of the size distribution of fine and ultra-fine particles emitted from vehicles on a busy road is investigated experimentally.
Ristovski, Zoran, Gramotnev, Galina
core +1 more source
, 2014 Citation: 'particle size distribution' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04431 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources