Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Exploring Particular Learner Factors Associated with South African Mathematics Learners’ Achievement: Gender Gap or Not [PDF]
, 2022 Sarah Bansilal, Thabo Lephoto
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Kettil Bruun is more relevant than ever. [PDF]
Nordisk Alkohol Nark, 2022 Hellman M.
europepmc +1 more source
A propósito del centenario del descubrimiento de la enfermedad de Chagas. Análisis cronológico de los principales hitos en la evolución de su conocimiento y control con particular énfasis en las contribuciones científicas uruguayas [PDF]
, 2010 Conti Díaz, A Ismael
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Autonomy in Japan: What does it Look Like? [PDF]
Asian Bioeth Rev, 2022 Akabayashi A, Nakazawa E.
europepmc +1 more source
The use of urodynamic studies to assess the effect of pharmacological agents with particular references to alpha-adrenergic blockade [PDF]
, 1984 David G. Thomas +3 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source