Results 171 to 180 of about 4,659,820 (378)
Electoral Rules and Legislative Particularism: Evidence from U.S. State Legislatures
American Political Science Review, 2016 Tanya Bagashka, Jennifer Hayes Clark
semanticscholar +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Desigualdades sociais e duas formas de particularismo na sociedade brasileira
Cadernos de Saúde PúblicaCom base em uma discussão de autores contemporâneos sobre a formação histórica do Brasil e sua incorporação ao projeto de sociedade moderna, o artigo identifica duas formas de particularismo o das diferenças e o das relações pessoais que na esfera ...
Jeni Vaitsman
doaj
Diversity Awareness in Medical Education: An Innovative Training with Visual Reflection Tools. [PDF]
Perspect Med Educ, 2023 Ang W +3 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Systematics of the Porricondylines (Diptera, Cecidomyiidae) with particular emphasis on the Brazilian Fauna [PDF]
Carolina de Almeida Garcia
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source