Results 91 to 100 of about 162,068 (290)

Particularities of metabolic syndrome in children

, 2022
Cojocari Svetlana, Mătrăgună Nelea
openalex   +2 more sources

PARTICULARITIES OF THE ASMR TECHNOLOGIES APPLICATION IN THE UKRAINIAN COMMERCIAL ADVERTISING IN THE CONTEXT OF GLOBAL MARKETING DEVELOPMENT TRENDS [PDF]

, 2021
О. Є. Антонова
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The particularity of being a fungus – I. Cellular components [PDF]

Biotemas, 2006
Morphological and reproductive characteristics have been used to define the four phyla (Chytridiomycota, Zygomycota, Ascomycota and Basidiomycota) that make up the Kingdom Fungi.
Rosana Leon Abrão, Péricles da S. Godinho, Nívea de F. Figueiredo, Elisandro Ricardo Dreschler-Santos, Claudia Groposo, Clarice Loguercio-Leite   +5 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The particularity of the geographical spreading endemical species ground-beetles genus Carabus on Caucasus

Юг России: экология, развитие, 2015
The Article is dedicated to particularity of the geographical spreading endemical species groundbeetles genus Carabus on Caucasus.
G. M. Abdurahmanov, M. Z. Magomedova
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

On «particularity» and «exceptionalism» of the United States of America

, 2020
Vladimir Pecheritsa
openalex   +1 more source

Particularities of cloning of Escherichia coli rpoBC-operon fragments in the pUC plasmids [PDF]

, 1987
Е. Б. Патон, I. V. Kroupskaya, A. N. Zhyvoloup   +2 more
openalex   +1 more source

Time Enough - Consequences of Human Microchip Implantation [PDF]

, 1997
Dr. Ramesh argues that microchip implantation is both possible and, for some purposes, desirable and suggests that now is the time to consider strategies for preventing potentially grievous intrusion into personal ...
Ramesh, Elaine M.
core   +1 more source