Results 101 to 110 of about 216,701 (377)

What is quantum mechanics trying to tell us? [PDF]

open access: yes, 1998
I explore whether it is possible to make sense of the quantum mechanical description of physical reality by taking the proper subject of physics to be correlation and only correlation, and by separating the problem of understanding the nature of quantum ...
Mermin, N. David
core   +2 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Singular and Particular

open access: yesCrítica (México D. F. En línea), 1968
Abstract
openaire   +3 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Serbs, the craziest of all – TV comedy show "Кursadžije" by Grand Production

open access: yesEtnoantropološki Problemi, 2009
This pa­per is the re­sult of re­se­arch do­ne on the TV co­medy show (se­ri­es) "Kur­sad­ži­je" by Grand Pro­duc­tion. The at­ten­tion is di­rec­ted to­wards un­der­stan­ding the mo­ti­ves of the Fool (buf­foon) which ap­pe­ars as the cha­rac­te­ri­stic
Marija Krstić
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The particularity of the geographical spreading endemical species ground-beetles genus Carabus on Caucasus

open access: yesЮг России: экология, развитие, 2015
The Article is dedicated to particularity of the geographical spreading endemical species groundbeetles genus Carabus on Caucasus.
G. M. Abdurahmanov, M. Z. Magomedova
doaj   +1 more source

Time-resolved homodyne characterization of individual quadrature-entangled pulses

open access: yes, 2004
We describe a simple and efficient setup to generate and characterize femtosecond quadrature-entangled pulses. Quantum correlations equivalent to about 2.5 dB squeezing are efficiently and easily reached using the non-degenerate parametric amplification ...
A. Ourjoumtsev   +32 more
core   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

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