Results 111 to 120 of about 162,068 (290)

Universities, social movements and market forces [PDF]

open access: yes, 2007
Universities have changed drastically over the past few decades. To understand and articulate what has happened, I make a stab at answering, however sketchily, the following questions: What forces have shaped universities over recent decades?
Sheehan, Helena
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Creation Stories: Stanley Hauerwas, Same-Sex Marriage, and Narrative in Law and Theology [PDF]

open access: yes, 2012
When I think about--members of my own staff who are incredibly committed, in monogamous relationships, same-sex relationships, who are raising kids together.
Copeland, Charlton C.
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Hegel's Nonfoundationalism: A Phenomenological Account of the Structure of Philosophy of Right [PDF]

open access: yes, 1994
In the Phenomenology Hegel insists there are no presupposed standards of truth: standards are internal. "Consciousness provides its own criterion from within itself, so that the investigation becomes a comparison of consciousness with itself"(PhdG 84 ...
Tunick, Mark
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

PARTICULARITY OF THE SURGICAL PROCEDURE IN ELDER PEOPLE

open access: yesZdravniški Vestnik, 2004
Life expectancy is getting longer and that is why a number of older patients who need surgical treatment increases. Due to accompanying illnesses and risks older patients need to be considered with careful ethical judgement of the necessity of the ...
Mihael Zajec
doaj  

Decolonial thinking and Europe: Decolonisation between particularity and universalism

open access: yesVerbum et Ecclesia
Colonisation continues to have a tremendous impact on large parts of the globe and not only on previously colonised countries. Many of the current geopolitical, economic and environmental challenges that the globe faces cannot be thought of without ...
Johann-Albrecht Meylahn
doaj   +1 more source

"Identity and Judgment: Five Theses and a Program" [PDF]

open access: yes, 1994
The theses and program below ask about judgment and tradition in a self-consciously plural world. The little program points down a path I am exploring in a pair of texts, one on notions of identity in the history of philosophy, and one on the identity of
Kolb, David
core  

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