Results 131 to 140 of about 216,701 (377)
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Theorising in urban and regional studies: negotiating generalisation and particularity
, 2020 K. Cox, E. Evenhuis
semanticscholar +1 more source
The Motivation Problem, Future Generations, and the Idea of “Leaving the Earth No Worse” [PDF]
, 2019 The author examines the problem of motivation about future generations. He argues that though many philosophers think that direct motivations are problematic for future generations only, they are not unproblematic for the current generations too, and ...
Huda, Kazi A. S. M. Nurul
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The Particularity of the Hermeneutics of God: A Response to Richard Kearney’s God-who-may-be [PDF]
, 2006 Lieven Boeve
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
PARTICULARITY OF THE SURGICAL PROCEDURE IN ELDER PEOPLE
Zdravniški Vestnik, 2004 Life expectancy is getting longer and that is why a number of older patients who need surgical treatment increases. Due to accompanying illnesses and risks older patients need to be considered with careful ethical judgement of the necessity of the ...
Mihael Zajec
doaj
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Education Between Ethical Universality and Cultural Particularity [PDF]
, 2007 Marcelo Sánchez Sorondo +2 more
openalex +1 more source