Results 221 to 230 of about 216,701 (377)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

A Case Report Depicting a Rare Neurosurgical Disease: Aggressive Meningiomatosis. [PDF]

J Clin Med
Tataranu LG.
europepmc   +1 more source

Approaches on the Particularities of the Motivational Dominants and Professional Performances within the Private Organizations [PDF]

, 2009
Marius Mitrache, Radu Ciorbagiu-Naon
openalex  

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

A Deep Learning-Enhanced Compartmental Model and Its Application in Modeling Omicron in China. [PDF]

Bioengineering (Basel)
Deng Q, Wang G.
europepmc   +1 more source

Applyng The Principles Of Corporate Governance In Central And Eastern European Countries, The National Characteristics And Particularities Of Corporate Governing In The Romanian Economy

, 2010
Zăpodeanu Daniela, Lucia Kolozsi, Liliana Durgheu   +2 more
openalex   +1 more source

The particularity and phenomenology of perceptual experience

, 2010
Susanna Schellenberg
semanticscholar   +1 more source

Phylogeographical particularity of the Mycobacterium tuberculosis Beijing family in South Korea based on international comparison with surrounding countries.

Journal of Medical Microbiology, 2010
Heeyoon Kang, T. Wada, T. Iwamoto, S. Maeda, Y. Murase, S. Kato, H. Kim, Young Kil Park   +7 more
semanticscholar   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Particularities of the imagistic diagnosis of the cervical-cerebral arteries dissection. Flow-splitter dissection

, 2010
Gabriel Boeru, Laurentiu Gutiu
openalex   +1 more source