Results 71 to 80 of about 162,068 (290)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

STUDY ON THE USEFULNESS OF CONCIEVING AND USING PATTERNS IN THE PROCESS OF INITIAL SELECTION AND OF THE FORMATION OF BEGINNERS GOUPS IN THE GAME OF HANDBALL

open access: yesSport şi Societate, 2017
The selection process is more and more encountered in all fields of activities, but nowhere is it so rigorously organized and programmed as in sports. It is a continuous process which aims at detecting, initiating, and maintaining young talented people ...
Stoian I.
doaj  

Particularity and Reflexivity in the Intentional Content of Perception

open access: yesTheoria, 2010
A significant part of perception is characterized by awareness of particular objects. Two ways of making precise this intuition have been proposed (Searle vs. Evans, Campbell and others).
Olga FERNÁNDEZ PRAT
doaj   +1 more source

Stage Left: A Review of Contingency, Hegemony, Universality: Contemporary Dialogues on the Left [PDF]

open access: yes, 2020
Reviews the three way conversation among Ernesto Laclau, Slavoj Zizek, and Judith Butler on leftist political theories of hegemony and universality and social change.
Maccannell, Juliet
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Cohesion and Particularity in the Spanish Dialect Continuum

open access: yesOpen Linguistics, 2018
This paper studies the degree of cohesion among varieties of Spanish, proposing an analysis of Spanish dialectal variation and the internal cohesion of varieties using the Varilex-R database (2016).
Fernández Francisco Moreno, Ueda Hiroto
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

THE SOCIAL PROTEST «WITH CHINESE PARTICULARITY»: THE SHIFTING VECTOR

open access: yesVestnik MGIMO-Universiteta, 2015
The article analyzes current spiritual-political and socio-economic situation in postreform China with the emphasis on newest tendencies in the social feeling and conscience.
V. A. Korsun
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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