Results 81 to 90 of about 126,332 (263)

Complex saddles of charged-AdS gravitational partition function

open access: yesJournal of High Energy Physics
In this paper, we consider the Euclidean partition function of uncharged and charged AdS d+1 black hole geometries in canonical and grand canonical ensemble for d ≥ 3.
Manishankar Ailiga   +2 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Affine symmetries for ABJM partition function and its generalization

open access: yesJournal of High Energy Physics
Partially motivated by the fact that the grand partition function of the ABJM theory or its generalization is expressed by a spectral operator enjoying symmetries of the Weyl group, it was found that the grand partition function satisfies the q-Painlevé ...
Sanefumi Moriyama, Tomoki Nosaka
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Exact large N expansion of mass deformed ABJM theory on squashed sphere

open access: yesJournal of High Energy Physics
In this paper we study the partition function of the mass deformed ABJM theory on a squashed three sphere. In particular, we focus on the case with the Chern-Simons levels being ±1 and apply a duality between this theory and the N $$ \mathcal{N} $$ = 4 U
Naotaka Kubo, Tomoki Nosaka, Yi Pang
doaj   +1 more source

A Parameter-Free Outlier Detection Algorithm Based on Dataset Optimization Method

open access: yesInformation, 2019
Recently, outlier detection has widespread applications in different areas. The task is to identify outliers in the dataset and extract potential information.
Liying Wang   +5 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

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