Results 111 to 120 of about 575,106 (294)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

From Quantum Curves to Topological String Partition Functions. [PDF]

open access: yesCommun Math Phys, 2023
Coman I, Pomoni E, Teschner J.
europepmc   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

3d expansions of 5d instanton partition functions

open access: yesJournal of High Energy Physics, 2018
We propose a set of novel expansions of Nekrasov’s instanton partition functions. Focusing on 5d supersymmetric pure Yang-Mills theory with unitary gauge group on ℂq,t−12×S1 $$ {\mathrm{\mathbb{C}}}_{q,{t}^{-1}}^2\times {\mathbb{S}}^1 $$, we show that ...
Fabrizio Nieri, Yiwen Pan, Maxim Zabzine
doaj   +1 more source

The partition function of a degenerate functional [PDF]

open access: yesCommunications in Mathematical Physics, 1979
The partition function of a degenerate quadratic functional is defined and studied. It is shown that Ray-Singer invariants can be interpreted as partition functions of quadratic functionals. In the case of a degenerate non-quadratic functional the semiclassical approximation to the partition function is considered.
openaire   +3 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Intersecting surface defects and instanton partition functions

open access: yesJournal of High Energy Physics, 2017
We analyze intersecting surface defects inserted in interacting four-dimensional N = 2 $$ \mathcal{N}=2 $$ supersymmetric quantum field theories. We employ the realization of a class of such systems as the infrared fixed points of renormalization group ...
Yiwen Pan, Wolfger Peelaers
doaj   +1 more source

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