Results 81 to 90 of about 1,112,271 (324)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Freely acting orbifolds of type IIB string theory on T 5
Journal of High Energy Physics, 2023 We study freely acting orbifolds of type IIB string theory on T 5 that spontaneously break supersymmetry from N $$ \mathcal{N} $$ = 8 to N $$ \mathcal{N} $$ = 6, 4, 2 or 0 in five dimensions.
George Gkountoumis +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
The rank of the semigroup of transformations stabilising a partition of a finite set
, 2014 Let $\mathcal{P}$ be a partition of a finite set $X$. We say that a full transformation $f:X\to X$ preserves (or stabilizes) the partition $\mathcal{P}$ if for all $P\in \mathcal{P}$ there exists $Q\in \mathcal{P}$ such that $Pf\subseteq Q$.
+7 more
core +1 more source
Maximum Independent Sets Partition of (n,k)-Star Graphs
Complexity, 2019 The (n,k)-star graph is a very important computer modelling. The independent number and chromatic number of a graph are two important parameters in graph theory.
Fu-Tao Hu
doaj +1 more source
Cardy limits of 6d superconformal theories
Journal of High Energy Physics, 2021 We explore the supersymmetric partition functions of 6d SCFTs on ℝ4 × T 2 with non-vanishing charges for compatible global symmetries. We utilize the elliptic genera for self-dual strings and compute the free energy of 6d SCFTs in the Cardy limit.
Kimyeong Lee, June Nahmgoong
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
3D N = 1 SYM Chern-Simons theory on the Lattice
, 2007 We present a method to implement 3-dimensional N = 1 SUSY Yang-Mills theory (a theory with two real supercharges containing gauge fields and an adjoint Majorana fermion) on the lattice, including a way to implement the Chern-Simons term present in this ...
A.G. Cohen +12 more
core +1 more source
On the Constant Partition Dimension of Some Generalized Families of Toeplitz Graph
Journal of MathematicsThe use of graph theory is prevalent in the field of network design, whereby it finds utility in several domains such as the development of integrated circuits, communication networks, and transportation systems. The comprehension of partition dimensions
Ali N. A. Koam +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source