Results 31 to 40 of about 6,806 (225)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Partition dimension of generalized Peterson and Harary graphs

open access: yes, 2021
© 2021. All Rights Reserved.The distance of a connected, simple graph (Formula presented) is denoted by d(α1, α2), which is the length of a shortest path between the vertices α1,α2 (Formula presented) V((Formula presented)), where V((Formula presented ...
Azeem, Muhammasd   +4 more
core  

Friendly bisections of random graphs

open access: yes, 2022
Resolving a conjecture of Füredi from 1988, we prove that with high probability, the random graph G ( n , 1 / 2 ) \mathbb {G}(n,1/2) admits a friendly
Asaf Ferber   +9 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Partition Dimension of Some Classes of Homogenous Disconnected Graphs

open access: yes, 2015
An ordered partition Π of the vertex-set resolves a (not necessarily connected) graph G if the representations of all vertices are distinct. The minimum k such that there is a resolving k-partition Π of G is called the partition dimension of G, and ...
Haryeni, Debi Oktia, Baskoro, Edy Tri
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Measurable tilings by abelian group actions [PDF]

open access: yes, 2023
Let $X$ be a measure space with a measure-preserving action $(g,x) \mapsto g \cdot x$ of an abelian group $G$. We consider the problem of understanding the structure of measurable tilings $F \odot A = X$ of $X$ by a measurable tile $A \subset X ...
Grebík, Jan   +3 more
core   +1 more source

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