Results 51 to 60 of about 63,650 (269)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A new class of infinite products, and Euler's totient
International Journal of Mathematics and Mathematical Sciences, 1994 We introduce some new infinite products, the simplest being(1−y)∏k=2∞∏j∈ϕk(1−ykqj)1/k=(1−y1−qy)1/(1−q),where ϕk is the set of positive integers less than and relatively prime to k, valid for |y|∧|qy| both less than unity, with q≠1.
Geoffrey B. Campbell
doaj +1 more source
Real-world applications of number theory [PDF]
ریاضی و جامعهThe above abstract has been extracted by the translator from the original article (J. Klaška, Real-world applications of number theory, South Bohemia Mathematical Letters, 25 no.
Rahim Rahmati-Asghar
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Classifiers, partitions, and measurements: Exploring the syntax and semantics of sortal classifiers
Glossa, 2019 In many languages, measure terms like item and kilo, as in two items of furniture and two kilos of rice, can be used either to partition the nominal denotation into countable units, or to measure a denotation without inducing a partition. These two types
Alan Bale, Jessica Coon, Nicholás Arcos
doaj +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Discrete Mathematics & Theoretical Computer Science, 2013 In this extended abstract we consider the poset of weighted partitions Π _n^w, introduced by Dotsenko and Khoroshkin in their study of a certain pair of dual operads.
Rafael González S. D'León +1 more
doaj +1 more source