Results 101 to 110 of about 214,292 (293)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Geoadditive latent variable modelling of count data on multiple sexual partnering in Nigeria [PDF]
The 2005 National HIV/AIDS and Reproductive Health Survey in Nigeria provides evidence that multiple sexual partnering increases the risk of contracting HIV and other sexually transmitted diseases.
Adebayo, Samson B. +2 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Governance in Organizational Expansion - Learning From Community Development Organizations [PDF]
, 2011 Community development organizations are dynamic nonprofits that adopt a range of proven strategies to revitalize neighborhoods so they are great places to live, work and play.
Ann Houston, Hilary Marcus
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Recycled Eco-Concretes Containing Fine and/or Coarse Concrete Aggregates. Mechanical Performance
Applied SciencesThis study analysed the effect of substituting different percentages of natural aggregate with recycled aggregate from concrete crushing, using a coarse fraction as well as a fine fraction.
Pablo Plaza +3 more
doaj +1 more source
Partnering for Phytomedicine Research
Issues in Science and Technology Librarianship, 2004 The Arid Lands Information Center (ALIC) is the Information Collection and Dissemination Unit for the Arizona Center for Phytomedicine Research (ACPRx), which received funding from the National Center for Complementary and Alternative Medicine and ...
Carla Long Casler
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source