Results 141 to 150 of about 1,901,965 (297)
BJPsych OpenAims: NICE guidelines (NG97) emphasize the importance of assessing the anticholinergic burden of medications in older adults. Anticholinergic side effects of medications can worsen constipation, urinary retention, sedation and confusion, exacerbating ...
Jessica May +4 more
doaj +1 more source
2011: Celebrating 10 Years of YEPP! [PDF]
, 2011 This booklet includes a series of case studies of the YEPP Local Programme Sites and the young people together with studies that demonstrate the unique partnership aspect, as well as the international dimension of the Youth Empowerment Partnership ...
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Piscataqua Region Environmental Planning Assessment Grant Program Summary Report (2015-2016) [PDF]
, 2020 Piscataqua Region Estuaries Partnership
core +1 more source
Working in partnership through early support: distance learning text: changing perceptions (book chapter) [PDF]
, 2007 This is a chapter from the distance learning text for the 'Working in Partnership through Early Support' accredited training programme.
Brown, Mark, Trimbee, Olivia
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Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
A political economy of environmental impact assessment in the Mekong region
Water Alternatives, 2016 Environmental Impact Assessment (EIA) is an issue of concern to governments, organized civil society groups, as well as business actors in the Mekong region.
Andrew Wells-Dang +7 more
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FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source