Results 201 to 210 of about 961,049 (288)

Self‐Assembled Hybrid Cell‐Enzyme Materials for Gas‐Powered Biocatalysis

Advanced Functional Materials, EarlyView.
Integrating living cells with programmable enzyme networks enables hybrid materials that convert gaseous feedstocks into chemical reducing power. These gas‐powered catalytic beads operate as modular, recyclable platforms for adaptive biocatalysis and sustainable synthesis.
Marius Stoeckle, Kersten S. Rabe, Christof M. Niemeyer   +2 more
wiley   +1 more source

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Identifying research priorities in adult intensive care in the United Kingdom: Results from a James Lind Alliance priority setting partnership. [PDF]

J Intensive Care Soc
Rose L, Wallace S, Abdillahi A, Borysik B, Bruce J, Burgess S, Crawford A, Gronlund T, Jarvis J, Jones J, Lacorcia L, Leighton S, Linstead G, Mach M, Negus-Fancey M, Newton-Smith S, Norman S, Ostermann M, Peng Y, Ramsay P, Sapsford D, Sharkey B, Tarpey M, Wade D, Watson J, Summers C.   +25 more
europepmc   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

The contribution of social science research to malaria prevention and control

Bulletin of the World Health Organization
Holly Ann Williams, Caroline Jones, Martin Alilio, Susan Zimicki, Inez Azevedo, Isaac Nyamongo, Johannes Sommerfeld, Sylvia Meek, Samba Diop, Peter B. Bloland, Brian Greenwood   +10 more
doaj   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Co-creating palliative care education across contexts: faculty experiences from a Ghana-Canada partnership for primary health care strengthening. [PDF]

Front Med (Lausanne)
Gyakobo MK, Amponsah AK, Owusu-Ansah M, Agbeko AE, Okyere P, Singh A, Nolen A, Wortzman R, Goldman A, Shamon S, Meuser J, Mazzotta P, Whitehead K, Bahammam S, Wilson J, Rouleau K, Wentlandt K.   +16 more
europepmc   +1 more source