Results 51 to 60 of about 1,122,829 (306)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

A Bourdieusian Analysis of Good Practice Partnerships: Implications for Private, Voluntary and Independent Early Childcare Leaders

Education Sciences, 2021
This article applies the theoretical lens of Bourdieu to explore leadership and the distribution of power between teachers and early childhood practitioners in the private voluntary and independent (PVI) sector in a good practice partnership.
Samantha McMahon, Nicola Firth, Andrew Youde   +2 more
doaj   +1 more source

Attorneys Must Not Enter Partnership Agreements Prohibiting Themselves from Representing Former Clients Upon Termination of Partnership. Dwyer v. Jung, 133 N.J. Super. 343, 336 A.2d 498 (Ch. 1975), appeal docketed, No. 3378-74, App. Div., June 18, 1975. [PDF]

, 1975
Three attorneys entered into a partnership agreement for the practice of law. Their agreement included a provision that assigned the partnership\u27s insurance carrier clients to individual partners upon the termination of the partnership and restricted ...
Schonfeld, Robert L.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Partnership or PR? Chevron in Bangladesh [PDF]

, 2012
Chevron are investing in communities and promoting human rights in Bangladesh, claiming that partnership with communities is not just good business practice, but crucial for social progress.
Gardner, Katy
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Partnerships in Practice [PDF]

, 2010
It was established in the previous chapter that an organisation’s accountability arrangements should depend on its function. What functions, though, do partnerships fulfil? This chapter proposes a functional classification of partnerships and outlines some of the main variations in partnership accountability.
openaire   +3 more sources

Reflection: Working Toward Peaceful, Healthy Communities

Interdisciplinary Journal of Partnership Studies, 2016
Family violence is a pervasive problem locally, nationally, and worldwide. Since 1990, staff from Saint Paul-Ramsey County (Minnesota) Public Health have worked with hundreds of community members and organizations in a unique partnership approach to ...
Donald L Gault
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Developing a toolkit for increasing the participation of black, Asian and minority ethnic communities in health and social care research

BMC Medical Research Methodology, 2022
Background It is recognised that Black, Asian and Minority Ethnic (BAME) populations are generally underrepresented in research studies. The key objective of this work was to develop an evidence based, practical toolkit to help researchers maximise ...
Azhar Farooqi, Karan Jutlla, Raghu Raghavan, Andrew Wilson, Mohammud Shams Uddin, Carol Akroyd, Naina Patel, Pamela Peggy Campbell-Morris, Aaisha Tasneem Farooqi   +8 more
doaj   +1 more source