Results 101 to 110 of about 102,508 (345)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Oxytocin in human intrauterine tissues at parturition [PDF]

open access: yes, 1995
The recent detection of oxytocin (OT) mRNA in human gestational tissues suggests that OT may be locally synthesized and released to act on the uterus as a local mediator in the mechanism of parturition.
Mauri, A   +3 more
core   +1 more source

15-Ketodihydro-PGF, Progesterone and Cortisol Profiles in Heifers after Induction of Parturition by Injection of Dexamethasone

open access: yesActa Veterinaria Scandinavica, 2001
In order to study rapid changes in 15-ketodihydro-PGF2α, cortisol and progesterone in the period preceding parturition in cattle, pre-term parturition was induced in 4 late pregnant heifers.
Parvizi N   +4 more
doaj   +1 more source

Q fever in pregnant goats: pathogenesis and excretion of Coxiella burnetii. [PDF]

open access: yesPLoS ONE, 2012
Coxiella burnetii is an intracellular bacterial pathogen that causes Q fever. Infected pregnant goats are a major source of human infection. However, the tissue dissemination and excretion pathway of the pathogen in goats are still poorly understood.
Hendrik-Jan Roest   +6 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Endocrinology of parturition in the pig [PDF]

open access: yes, 1979
Endocrine and physiological events that precede and accompany parturition in the sow occur in a sequential fashion starting with a slow increase in estrogens from about three weeks prior to parturition.
Parvizi, Nahid   +13 more
core   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

ESTIMATION OF MOOSE PARTURITION DATES IN COLORADO: INCORPORATING IMPERFECT DETECTIONS [PDF]

open access: yes, 2020
Researchers and managers use productivity surveys to evaluate moose populations for harvest and population management purposes, yet such surveys are prone to bias.
Bergman, Eric J.   +2 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Induction of Parturition with Aglepristone in the Majorera Goat [PDF]

open access: yes, 2011
This study assessed the efficacy of aglepristone at inducing parturition in pregnant goats. Six experimental groups were defined: group A-5 (n = 12), group A-3.3 (n = 12), group A-2.5 (n = 12) and group A-1.5 (n = 12) in which goats were injected SC once
J Vilar   +15 more
core   +1 more source

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