Results 21 to 30 of about 56,444 (289)

Changes in the Th1 : Th2 Cytokine Bias in Pregnancy and the Effects of the Anti-Inflammatory Cyclopentenone Prostaglandin 15-Deoxy-Δ12,14-Prostaglandin J2

Mediators of Inflammation, 2012
Pregnancy is a complex immunological state in which a bias towards T helper 2 (Th2) protects the fetus. Evidence suggests that proinflammatory cytokines increase the risk of poor neonatal outcome, independently of the direct effect of preterm labour. The
Lynne Sykes, David A. MacIntyre, Xiao J. Yap, Sathana Ponnampalam, Tiong Ghee Teoh, Phillip R. Bennett   +5 more
doaj   +1 more source

Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition

Journal of Lipid Research, 2022
Human parturition is associated with massive arachidonic acid (AA) mobilization in the amnion, indicating that large amounts of AA-derived eicosanoids are required for parturition. Prostaglandin E2 (PGE2) synthesized from the cyclooxygenase (COX) pathway
Fan Zhang, Kang Sun, Wang-Sheng Wang
doaj   +1 more source

The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour

Mediators of Inflammation, 2012
Pregnancy is a unique immunological state in which a balance of immune tolerance and suppression is needed to protect the fetus without compromising the mother.
Lynne Sykes, David A. MacIntyre, Xiao J. Yap, Tiong Ghee Teoh, Phillip R. Bennett   +4 more
doaj   +1 more source

NFκB and AP-1 Drive Human Myometrial IL8 Expression

Mediators of Inflammation, 2012
The uterine expression of the chemokine IL8 increases dramatically with the onset of labour both at term and preterm. The IL8 promoter contains binding sites for the transcription factors nuclear factor-kappa B (NFκB), activator protein-1 (AP-1), and ...
Shirin Khanjani, Vasso Terzidou, Mark R. Johnson, Phillip R. Bennett   +3 more
doaj   +1 more source

Pregnancy in the Unicornuate Uterus and Non-Communicating Rudimentary Horn [PDF]

Iranian Journal of Medical Sciences, 2023
Congenital uterine abnormalities affect 1-10% of the general population and are caused by defective paramesonephric duct fusion or resorption during embryonic stages.
Salmeh Dadgar, Maliheh Mahmoudinia, Neda Davaryari   +2 more
doaj   +1 more source

Changes of Serum Calcium Concentration, Frequency of Ruminal Contraction and Feed Intake Soon after Parturition of Dairy Cows Fed Difructose Anhydride III [PDF]

Asian-Australasian Journal of Animal Sciences, 2015
Requirements to control the large decrease in serum calcium (Ca) due to parturition and to increase the feed intake soon after parturition have been well accepted in dairy cows.
S. Wynn, M. Teramura, T. Sato, M. Hanada
doaj   +1 more source

From conception to recruitment: Nutritional condition of the dam dictates the likelihood of success in a temperate ungulate

Frontiers in Ecology and Evolution, 2023
Maternal effects are the influence of maternal phenotype and the maternally-provided environment on the phenotype (i.e., expression of traits) of offspring. Frequently, maternal effects are manifest both before and after parturition.
Sydney Lamb, Sydney Lamb, Brock R. McMillan, Madelon van de Kerk, Madelon van de Kerk, Paul B. Frandsen, Kent R. Hersey, Randy T. Larsen   +7 more
doaj   +1 more source

Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract

Nature Communications
Lactobacillus species dominance of the vaginal microbiome is a hallmark of vaginal health. Pathogen displacement of vaginal lactobacilli drives innate immune activation and mucosal barrier disruption, increasing the risks of STI acquisition and, in ...
Alexiane Decout, Ioannis Krasias, Lauren Roberts, Belen Gimeno Molina, Chloé Charenton, Daniel Brown Romero, Qiong Y. Tee, Julian R. Marchesi, Sherrianne Ng, Lynne Sykes, Phillip R. Bennett, David A. MacIntyre   +11 more
doaj   +1 more source

Expression of C–C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition

The Journal of Reproduction and Development, 2019
In bovine placentomes, the inflammatory response is considered important for the detachment of the fetal membrane from the caruncle after parturition. Glucocorticoids, a trigger of the onset of parturition, facilitate functional maturation of placentomes
Hiroki HIRAYAMA, Ryosuke SAKUMOTO, Keisuke KOYAMA, Taichi YASUHARA, Taito HASEGAWA, Ryo INABA, Takashi FUJII, Akira NAITO, Satoru MORIYASU, Soichi KAGEYAMA   +9 more
doaj   +1 more source

Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution

Nature Communications, 2023
The timely onset of female parturition is a critical determinant for pregnancy success. The highly heterogenous maternal decidua has been increasingly recognized as a vital factor in setting the timing of labor.
Meng Liu, Mengjun Ji, Jianghong Cheng, Yingzhe Li, Yingpu Tian, Hui Zhao, Yang Wang, Sijing Zhu, Leilei Zhang, Xinmei Xu, Gen-Sheng Feng, Xiaohuan Liang, Haili Bao, Yedong Tang, Shuangbo Kong, Jinhua Lu, Haibin Wang, Zhongxian Lu, Wenbo Deng   +18 more
doaj   +1 more source