Integration of Ustekinumab Biosimilars into Inflammatory Bowel Disease Care: Evidence, Implementation, and Patient-Centered Considerations. [PDF]
Piche SL +4 more
europepmc +1 more source
Not All Missing Data are Equal: Choosing the Right Imputation Method for Binary Datasets
ABSTRACT Missing binary predictors are common in reliability, quality control, and industrial decision systems, yet imputation methods are often chosen by convenience rather than evidence. We conduct a Monte Carlo study comparing mode substitution, sequential hot‐deck, missForest, MICE, and KNN with three neighbourhood sizes under MCAR, MAR, and MNAR ...
Manuel Delfino, Fabio Rapallo
wiley +1 more source
Final analysis of the FeDeriCa phase III study: long-term efficacy, safety and pharmacokinetics of the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection, plus chemotherapy, in HER2-positive early breast cancer. [PDF]
Jackisch C +14 more
europepmc +1 more source
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues +6 more
wiley +1 more source
NextLongIso: a comprehensive Nextflow pipeline for multi-dimensional long-read RNA-seq analysis. [PDF]
Tan J, Wu Y, Sun Y.
europepmc +1 more source
ABSTRACT The increasing integration of distributed energy resources demands enhanced coordination between transmission system operators (TSOs) and distribution system operators (DSOs) to maintain reliable grid operation. Traditional approaches rely on hierarchical or distributed optimization schemes for power flow management, but these methods either ...
Janis Adamek +4 more
wiley +1 more source
Antiretroviral Treatment Switch Among Treatment-Experienced People with HIV. [PDF]
Chastek B +7 more
europepmc +1 more source
Practical Methodology for Developing Visions for Carbon‐Neutral Cities and Communities
ABSTRACT Cities and communities play important roles in sustainable development and climate change mitigation. This study presents a novel framework for developing carbon‐neutral visions for cities and communities. We established five “principles,” investigated options encompassing four parameters (management, goal setting, actions, and quantification),
Kei Gomi +4 more
wiley +1 more source

