Results 41 to 50 of about 167,905,385 (213)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Reliability of systems with randomly varying parameters by the path integration method [PDF]

, 2011
The paper considers a first passage time reliability problem for systems subjected to multiplicative and additive white noises. For numerical calculations of the reliability function and the first passage time the path integration method is properly ...
Yurchenko, Daniil, A. Naess, Naess, Arvid, O. Batsevych, Batsevych, Oleg, D. Iourtchenko   +5 more
core   +1 more source

Subjective expansion of extended time-spans in experienced meditators

Frontiers in Psychology, 2015
Experienced meditators typically report that they experience time slowing down in meditation practise as well as in everyday life. Conceptually this phenomenon may be understood through functional states of mindfulness, i.e. by attention regulation, body
Marc eWittmann, Simone eOtten, Eva eSchötz, Anna eSarikaya, Hanna eLehnen, Han-Gue eJo, Han-Gue eJo, Niko eKohls, Stefan eSchmidt, Stefan eSchmidt, Karin eMeissner   +10 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Deep boundary current disintegration in Drake Passage [PDF]

, 2013
The fate of a deep boundary current that originates in the Southeast Pacific and flows southward along the continental slope of South America is elucidated. The current transports poorly ventilated water of low salinity (a type of Pacific Deep Water; PDW)
Waterman, Stephanie N., Sheen, Katy L., David A. Smeed, Thurnherr, Andeaus M., Smeed, David A., Thurnherr, Andreas M., Waterman, Stephanie, Stephanie Waterman, Meredith, Michael M., Er Brearley, Katy L. Sheen, Naviera Garabato, Alberto C., Meredith, Michael P., Kevin G. Speer, Naveira Garabato, Alberto C., Speer, Kevin G., J. Alex, Alberto C. Naveira Garabato, Andreas M. Thurnherr, Michael P. Meredith, Brearley, J. Alexander, Garabato, A., Sheen, K., Speer, K., Meredith, M., Brearley, J., Thurnherr, A., Waterman, S., Smeed, D.   +28 more
core   +1 more source

First passage times of charge transport and entropy change

Memories - Materials, Devices, Circuits and Systems
All real physical processes, including of the first-passage time, occur with a change in entropy. This circumstance is not taken into account when studying the first-passage time, but is illustrated in this article using the example of electron transfer ...
V.V. Ryazanov
doaj   +1 more source

Passage of time judgments are not duration judgments: Evidence from a study using Experience Sampling Methodology

Frontiers in Psychology, 2016
This study examined relations between passage of time judgments and duration judgments in everyday life, in young and elderly people, with an Experience Sampling Method (ESM).
SYLVIE eDROIT-VOLET, John eWearden
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source